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Example sentences for: spindles
How can you use “spindles” in a sentence? Here are some example sentences to help you improve your vocabulary:
Their effectiveness in cancer chemotherapy is thought to be due to their ability to reduce the dynamics of microtubules in mitotic spindles, thus preventing spindle assembly and interrupting the normal movement of sister chromatids toward the spindle poles [ 3 4 5 6 7 8 9 ] . Tubulin, a 100 kDa αβ heterodimer, is structurally heterogeneous, with seven genes encoding α-tubulin and β-tubulin isotypes.
Discharge frequencies found for primary muscle spindles in the present study are also similar to those for 1° afferents in other muscles with intact γ-innervation [ 9 16 17 ] and without γ-innervation [ 18 19 20 ] . In these studies, the 1° muscle spindles were found to possess the greatest sensitivity to changes in velocity.
The dynamic sensitivities of the receptors were found to correspond to the ranges of discharge frequencies of afferents characterized by other investigators [ 2 9 11 ] . Matthews [ 10 ] found that de-efferented 1° muscle spindles in the soleus muscle of the cat responded to varied velocity changes (1.
The location and numbers of intercostal muscle mechanoreceptors suggest that they mediate the transduction of chest wall contractile mechanics [ 1 2 3 ] . Intercostal muscle spindles have been identified histologically [ 3 ] . These afferents increase their discharge frequency during inspiration and decrease their activity during expiration [ 3 ] . Intercostal muscle mechanoreceptors enter the spinal cord through the thoracic dorsal roots [ 3 ] . These chest wall mechanoreceptors are responsible for segmental and intersegmental proprioceptive feedback from the intercostal muscles.
However, it has been reported recently that morphologically normal M I spindles are formed but further meiotic progression does not occur in porcine oocytes matured in a cytochalasin B-containing medium [ 38].
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