Example sentences for: spindle

How can you use “spindle” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The Bub2/Bfa1 GTPase-activating protein (GAP) complex inhibits the MEN and cytokinesis in response to DNA damage and spindle misorientation ( [ 32 ] ; reviewed in [ 33 ] ). bub2Δ and CDC14 TAB 6-1cells show similar chromosome instability as wild-type cells.

  • Tem1 recruits Cdc15 to the spindle pole body, which in turn recruits and phosphorylates the Dbf2/Mob1 protein kinase complex, thereby switching it on [ 2 14 15 16 17 ] . The Tem1-signaling pathway eventually triggers disassembly of the RENT complex, enabling the release of Cdc14 (and a portion of Sir2) from Net1.

  • First, cohesion close to the centromere facilitates bi-orientation of chromosomes, such that each chromosome becomes attached to the two poles of the spindle [6].

  • The presence of sleep spindle should not be defined unless it is of at least 0.5 sec duration, i.e., one should be able to count 6 or 7 distinct waves within the half-second period.

  • Ndc10 forms part of a structure known as the kinetochore, which forms around the centromere and is responsible for the attachment to the spindle; establishment and maintenance of cohesion at pericentric regions may therefore rely on both the centromere sequence and kinetochore function [13,20].


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