Example sentences for: spindle

How can you use “spindle” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Kinesins having these domain may be involved in actin-MT cooperation during processes such as vesicle and organelle transport, spindle rotation and nuclear migration [ 65].

  • The spindle, which is composed of microtubules, pulls the chromatids apart so that two complete sets of chromosomes are gathered together at each pole of the cell, which can then divide.

  • During the standardization, all 35 melanomas (including one spindle cell melanoma and one clear cell melanoma) were immunoreactive with 'the cocktail'.

  • The MATs are predicated upon the coordinated activities of the spindle checkpoint [ 16 17 ] , the anaphase-promoting complex (APC) or cyclosome [ 18 19 ] , the proteasome [ 20 21 ] , and the cohesion-complex proteins involved with chromosome cohesion and separation [ 22 23 24 ] . Alterations in the temporal sequence of these coordinated activities may potentially predispose cells to faulty chromosome segregation.

  • After replication, the chromosomes (now comprising two chromatids) align at the center of the cell, and are attached to a structure known as the spindle apparatus.


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