Words similar to spermatogenesis
Example sentences for: spermatogenesis
How can you use “spermatogenesis” in a sentence? Here are some example sentences to help you improve your vocabulary:
Follicle stimulating hormone (FSH) regulates spermatogenesis through the somatic Sertoli cells of the testis [ 1 ] . Sertoli cells act as "nursing" cells and supplies germ cells with energy and controls the biochemical environment in which they develop [ 2 ] . Among the FSH-regulated functions are increased glucose uptake and oxidation.
Our finding of an increased rate of germ cell apoptosis in 21 and 30 days old ABP-TG mice as compared to controls is consistent with the possibility that the reduced fertility (reduced germ cell number) seen in the ABP-TG mice during adulthood may be due to increased apoptosis of germ cells during the first wave of spermatogenesis in the pubertal period.
, [ 10 12 13 14 15 ] ]. It is thought to regulate spermatogenesis and sperm maturation by maintaining high androgen levels in the testis and epididymis [ 16 17 ] and has been proposed as a biochemical marker for Sertoli cell function and formation of blood-testis barrier [ 12 18 ] . More recently, cell surface receptors for ABP and its liver-derived homolog sex hormone-binding globulin (SHBG) were identified in several androgen target tissues, suggesting that these extracellular steroid-binding proteins may have a much broader, hormone-like function [ 19 20 21 ] .
Indeed, p53 controls the low-level damage-dependent premeiotic checkpoint which facilitates DNA repair during spermatogenesis [ 25 ] . Gametogenesis is inherently error-prone [ 26 ] and subject to mutations [ 27 ] . Nevertheless, it is imperative to avoid genotoxic complications that could become integrated into the germline.
Our earlier findings including a reduced number of elongated spermatids in the ABP-TG mice [ 26 ] also support the notion that higher than physiological concentrations of ABP affect spermatogenesis indirectly, through sequestration of androgens; the transformation of round spermatids to elongated spermatids is known to be the main androgen-dependent step in spermatogenesis [ 35 36 37 ] .
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