Words similar to speckles
Example sentences for: speckles
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Nearly all nuclei (95%) contained small, numerous Rad26-GFP speckles, and roughly 50% of these nuclei also contained one or two very bright Rad26-GFP spots.
The mutated proteins are located in cytoplasmic speckles similar to the N346 NLSmut1and N346 NLSmut3(Fig 7B).
These data link the bright, Rad26-GFP spots with the cell cycle arrest activities of the DNA damage checkpoint, and suggest that Rad26-GFP speckles play a role in recovery.
These results suggest that the speckles could be associated with DNA repair and recovery activities, while the spots could be associated with cell cycle arrest.
These speckles are different than the larger, less numerous dots (6 on average) that we observed in untreated, cycling cells (compare Figure 1Bwith Figure 5A).