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Example sentences for: speckles

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Rad26-GFP Spots are Associated with Cell Cycle Arrest, and Speckles are Associated with Recovery
After damage, Rad26-GFP localization to speckles may correspond to the direct interaction of Rad26 with sites of damage.
Further, we do not know whether the cytoplasmic speckles formed by GFP-N346 NLSmut1and GFP-N346 NLSmut3are in any way related to the nuclear speckles of wild-type GFP-N346.
Objects in nuclei recognized by antibodies specific for phosphoprotein epitopes, cytoplasmic IFs, or both, have been reported in glial and neuronal cells, in situ and in vitro . The nuclear structures appear spherical or rod-like and may have a positional relationship with nuclear pores [ 1 2 3 4 ] . Morphologically, these structures appear similar to the nuclear "speckles" that are thought to be storage sites for RNA splicing factors [ 5 6 7 ] . However, while intermediate filament (IF) phosphoproteins could be components of nuclear speckles, they are immunologically distinct.
Second, approximately half of Bleomycin-treated cells also contained one or two bright, nuclear spots (Figure 5B; arrow denotes the speckles that formed in these cells).