Example sentences for: slp-

How can you use “slp-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Recent data argue that Itk interacts directly with Slp-76 and Grb2 to participate in a LAT-nucleated T cell signaling complex involved in PLC-γ activation [ 5, 29].

  • Recent data suggests that phosphorylation of the T cell adaptor molecule SLP-76 occurs after stimulation of T cells with altered peptide ligands in a Fyn-dependent manner that is independent of the adaptor molecule LAT [ 39, 40].

  • The second class of phosphotyrosine dependent adaptors exemplified by proteins such as Cas, Dok, IRS-1 and 2 or Slp-76, as cytosolic adaptors, or LAT, TRIM or SIT as membrane anchored adaptors, also require the activation of upstream signals by tyrosine kinases for their function.

  • Notably, Rlk has also been found to be capable of phosphorylating SLP-76 [ 41].

  • Adaptor proteins that regulate tyrosine kinase signaling pathways fall into two major categories, those primarily with protein/protein interaction domains such as SH2, SH3, PTB, and PH domains, exemplified by the adaptor proteins c-crk, nck and grb-2, and those that are primarily tyrosine phosphorylated, exemplified by proteins such as Cas, Dok, IRS-1 and 2, Slp-76, LAT, TRIM or SIT.


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