Words similar to slp-
Example sentences for: slp-
How can you use “slp-” in a sentence? Here are some example sentences to help you improve your vocabulary:
Adaptor proteins that regulate tyrosine kinase signaling pathways fall into two major categories, those primarily with protein/protein interaction domains such as SH2, SH3, PTB, and PH domains, exemplified by the adaptor proteins c-crk, nck and grb-2, and those that are primarily tyrosine phosphorylated, exemplified by proteins such as Cas, Dok, IRS-1 and 2, Slp-76, LAT, TRIM or SIT.
Recent data argue that Itk interacts directly with Slp-76 and Grb2 to participate in a LAT-nucleated T cell signaling complex involved in PLC-γ activation [ 5, 29].
The second class of phosphotyrosine dependent adaptors exemplified by proteins such as Cas, Dok, IRS-1 and 2 or Slp-76, as cytosolic adaptors, or LAT, TRIM or SIT as membrane anchored adaptors, also require the activation of upstream signals by tyrosine kinases for their function.
Notably, Rlk has also been found to be capable of phosphorylating SLP-76 [ 41].
Recent data suggests that phosphorylation of the T cell adaptor molecule SLP-76 occurs after stimulation of T cells with altered peptide ligands in a Fyn-dependent manner that is independent of the adaptor molecule LAT [ 39, 40].