Words similar to skp

Example sentences for: skp

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Consistent with this idea, biochemical studies based on the crystal structure of the human SKP1-SKP2 complex revealed cooperation of the SKP2 F-box with an adjacent region in binding of SKP1 [ 28 ] . Consistent with this finding, certain truncation mutants of the budding yeast F-box proteins Grr1p and Cdc4p interact poorly with Skp1p, despite the retainment of their F-boxes [ 30 31 ] . On the other hand, the F-box of Pop1p is essential for Rum1p degradation (Fig.
In contrast, the majority of MIB-treated cells showed strong p27 expression, while only few cells were positive for SKP2.
SCF complexes are E3s composed of the Cullin family member Cul1 (Cdc53 in S. cerevisiae ), as well as, Skp1, Roc1 (also called Rbx1 or Hrt1) and one of the numerous F-box proteins that act as a receptor for the substrate (for review see [ 2 ] ).
In contrast, CDK2 and tubulin levels remained stable at all time points of SKP2 overexpression (Fig.
The complete SKP2 cDNA or a mutant lacking the F-box (SKP2-ΔF) were cloned into a modified pcDNA3 plasmid providing an N-terminal Myc epitope tag and the human lamin B leader sequence.