Words similar to skipping
Example sentences for: skipping
How can you use “skipping” in a sentence? Here are some example sentences to help you improve your vocabulary:
At least half of the reported cases of intergenic splicing result from skipping the last exon of the upstream gene and the first exon of the downstream gene [ 32 33 39 ] . This is thought to be due to the lack of donor and acceptor splice sites in these exons, respectively.
As reported previously, the long RT-PCR method identified six samples with transcripts skipping exons 18, 31, 46, 49, 56 or 58 that were caused by nucleotide substitutions at splice sites [ 8 ] . In another patient, skipping of exon 51 was discovered to be due to a silent mutation within the exon, possibly affecting a splicing enhancer binding site [ 19 ] . Here we report abnormal fragments seen after Taq I digestion of the exon 29-52 amplicons (Fig.
For example, exon-skipping mutations in the central region of the gene, exons 24-32, cause severe phenotypes or neonatal presentations [ 8 ] . But there are exceptions, only four of the many other mutations in this region cause severe phenotypes, while one mutation predicted to lead to skipping of exon 24 was found in a patient with classic MFS [ 5 ] . In contrast, most cysteine substitutions cause classic MFS with a high frequency of lens dislocation, although some patients in our study did not meet the Ghent criteria for diagnosis of MFS [ 9 ] . Amino-acid substitutions not disrupting disulfide bonds may be associated with fibrillinopathies other than MFS, although mutations in the calcium-binding consensus sequence have been reported in individuals with classic MFS [ 5 10 11 12 ] . It is clear from the studies reported so far, that genotype-phenotype correlations are not straight-forward for FBN1 mutations.
McCain doesn't need to persuade the media that his reasons for skipping Ames were morally sound.
These data indicate that one has to be extremely careful when correlating exon skipping events to secondary structure predictions.
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