Example sentences for: skeletal-type

How can you use “skeletal-type” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, the protocol accurately measures the immobilization-resistant charge movements that are known to be required for skeletal-type EC coupling [ 31, 40].

  • 4B, we failed to detect EC coupling in these KO cells transfected with fs-α 1S . In summary, the EC coupling expressed by fs-α 1S is strictly skeletal-type and requires RyR1 and DHPR β1a.

  • Thus we are certain that the EC coupling expressed by fs-α 1S is mechanistically similar to control skeletal-type EC coupling but limited in magnitude by a comparatively lower density of functional DHPRs that are assembled in cells expressing fs-α 1S . It is conceivable that the functional integrity of the fragmented α 1S protein is maintained in part by the β subunit of the DHPR which spans both halves of the α1 pore subunit by binding to the I-II loop and the C-terminus [ 35 36 ] . Consistent with this explanation, we failed to detect EC coupling recovery when fs-α 1S was expressed in β1-null myotubes.

  • While this subunit is clearly non-essential for activation of the L-type Ca 2+channel and for triggering skeletal-type EC coupling, γ 1 appears to specifically modulate the Ca 2+channel function of the skeletal DHPR.


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