Example sentences for: six-transmembrane

How can you use “six-transmembrane” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As a member of the six-transmembrane domain superfamily of ion channels, VR1 most likely assembles into tetrameric complexes.

  • For those ion channels within this superfamily for which stoichiometry has been directly examined, all have been shown to be composed of four six-transmembrane domain subunits or pseudosubunits, with auxiliary subunits sometimes present as well [ 22 ] . An initial characterization of VR1 channels expressed in Cos and CHO cells has recently revealed that, under certain conditions, they run as multimers on pseudo-native (PFO) gels, with tetramers being one of the primary bands observed [ 23 ] . Thus, like other six membrane spanning domain channels, VR1 almost certainly forms as a tetramer; whether it combines with homologous subunits to form heteromeric channels remains to be determined.

  • Drosophila polarity gene Wunen-2 [ 31 32 ] . PAP2b/VCIP encodes 311 amino acid residues, contains a single N-glycosylation site, a consensus lipid phosphatase motif (KPSXXXRPH), an RGD cell attachment motif, six-transmembrane channel-like structure, and displays Mg ++independent lipid phosphatase activity in transfected 293T cells [ 32 ] . Both N- and C-terminus segments of PAP2b/VCIP are located inside the cytoplasm.

  • Among the six-transmembrane channels, there are two additional families.

  • There is 78-98% amino-acid sequence identity between the six-transmembrane K +-channel gene products in Drosophila and their orthologs in Anopheles , a value significantly greater than what other studies have calculated (62% identity and 56% in separate studies [ 16 17 ] ) as a mean value for sequence identity between orthologs in these two organisms.


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