Words similar to six-helix

Example sentences for: six-helix

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In summary, the results presented here suggest that treatment of HIV-1 with CAP leads to conformational changes in the envelope glycoproteins, ultimately resulting, in the absence of target cell membranes, in the formation of gp41 six-helix bundles.
Thus, it seems likely that the detection of gp41 six-helix bundles in untreated HIV-1 using the virion capture assay was due to their spontaneous formation during prolonged incubation of HIV-1 in these tests.
In the experiments described above evidence for the formation of gp41 six-helix bundles was obtained from capture of CAP, CD4 and CCR5 S-peptide treated virus particles, respectively, onto wells coated with mAb NC-1.
The sandwich ELISA for gp41 six-helix bundles was performed as described [ 37 45 ] . HIV-1 IIIB and BaL virus preparations, respectively, treated with distinct anionic polymers, were precipitated with 3% polyethylene glycol 6000 (PEG) in order to separate virus particles from excess compounds.
Engagement of the gp120 coreceptor binding site with a tyrosine sulfated peptide from the N-terminus of the coreceptor CCR5 [ 25 ] , shown to inhibit infection by CCR5-dependent, but not CXCR4-dependent, HIV-1 isolates, was sufficient to increase the expression of the gp41 six-helix bundles in HIV-1 BaL virus particles (Fig.