Words similar to situ
Example sentences for: situ
How can you use “situ” in a sentence? Here are some example sentences to help you improve your vocabulary:
Investigations of intermediate filaments (IF) in the nucleus have focused on lamins (see Goldman for a current review) [ 8 ] , but many reports of in situ nuclear localization of cytoplasmic IFs also exist, e.g., vimentin in association with nuclear DNA in cultured fibroblasts [ 9 10 ] , and an estrogen-sensitive cytokeratin association with nuclear DNA in human breast cancer cells [ 11 ] .
[ 27 ] found by in situ hybridization that 1.0% of fibers expressed only IIb and 8.8% coexpressed the IIx and IIb isoforms.
By applying in situ hybridization, Tuck and colleagues identified breast tumor cells as a source of OPN [ 13 ] . Using a semiquantitative scoring system to evaluate immunohistochemical staining, these investigators found a correlation between OPN positivity (defined as >33% of tumor cells in a section staining for OPN) in lymph node-negative primary breast carcinomas and patient survival, suggesting that tumor cells with elevated OPN levels may behave differently with regard to disease progression [ 13 ] . Another recent study showed immunohistochemically that while OPN protein is expressed weakly in normal breast tissue, OPN is expressed strongly (>50% tumor cell staining) in pregnant/lactating tissue and in the majority (66%) of breast carcinomas.
To begin addressing the biological and biochemical characterization of inducible PP1α, we next localized this protein in situ using immunohistochemistry.
Microarray data are useful to identify experiments where the RNA in situ hybridization failed but the given gene is highly expressed.
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