Words similar to sitosterolemic
Example sentences for: sitosterolemic
How can you use “sitosterolemic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Such lines will be useful in demonstrating that the variant sterolin-1 protein is responsible for causing sitosterolemia, but will allow comparisons between animals that are hypertensive and those that are hypertensive and sitosterolemic.
All of these strains are homozygous mutant for Gly583Cys in sterolin-1, encoded by Abcg5 . This mutation is not present in rats that were not sitosterolemic, even though one of these was hypertensive (the GH rat).
However, it is not known whether the atherosclerosis in sitosterolemic patients with hypertension is accelerated, relative to those affected individuals with lower blood pressures.
However, a literature search revealed that a few strains of rats, studied primarily for investigation of hypertension and stroke, have been reported to be sitosterolemic as well [ 15 16 ] . We hypothesised that these rat strains may be mutated in either Abcg5 or Abcg8 . Tissue (and plasma) plant sterol levels in the Wistar Kyoto (WKY) rat, the spontaneously hypertensive rat (SHR) and the stroke-prone spontaneously hypertensive rat (SHRSP) were significantly higher than in Wistar and WKA rats fed either a regular chow diet or diets that have higher plant sterols and these were correlated with increased death, or red cell hemolysis etc. [ 15 16 17 18 19 20 21 22 ] . Dietary sterol absorption rates were increased, with a decrease in sterol excretion [ 16 ] , characteristics similar to that observed in sitosterolemic patients.
Our analyses confirmed that WKY, and SHR are sitosterolemic on a chow diet, but neither the control strains, nor the GH rat showed any significant differences.
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