Example sentences for: sitosterolemic

How can you use “sitosterolemic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Our analyses confirmed that WKY, and SHR are sitosterolemic on a chow diet, but neither the control strains, nor the GH rat showed any significant differences.

  • However, one change, G1754T in exon 12 was identified that led to a coding change of Gly583Cys in sterolin-1 ( Abcg5 ). This change was found only in rat strains that were confirmed to be sitosterolemic (WKY, SHR and SHRSP), but not in any of the other strains screened (SD, Wistar, WKA, GH or BN).

  • We interrogated this region for genetic variations and found a correlation between sitosterolemic strains and a missense mutation in Abcg5 .

  • All of these strains are homozygous mutant for Gly583Cys in sterolin-1, encoded by Abcg5 . This mutation is not present in rats that were not sitosterolemic, even though one of these was hypertensive (the GH rat).

  • Three rat strain, WKY, SHR and SHRSP, that are hypertensive are also sitosterolemic.


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