Words similar to single-point

Example sentences for: single-point

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RNA viruses form highly polymorphic clouds of mutants, so-called quasispecies [ 1 2 3 ] . At viral loads of 10 8or more virions in an infected host, viral quasispecies in vivo often contain all possible single-point mutants from the consensus sequence, as well as a sizeable fraction of two- or three-point mutants [ 4 ] . Besides their importance as pathogens, RNA viruses have in recent years also become one of the main tools for experimental verification of theoretical population genetics and evolutionary theory in general (reviewed in [ 3 ] ). This line of research can draw on a substantial body of literature on the theory of quasispecies dynamics and its relation to standard population genetics [ 5 6 7 8 9 10 11 12 13 14 15 16 ] .
The sampling area of single-point laser Doppler probes is dependent upon their geometry, but is usually between 1 and 3 mm 3and, because of the spatial heterogeneity of tissue blood flow, single measurements may not be representative of overall local cutaneous blood flow [ 22, 23].
Conventional single-point laser Doppler flowmetry (LDF) has been successfully used to assess the cutaneous microcirculation in a variety of clinical applications.
The technique has been validated against flow models, conventional single-point laser Doppler flowmetry and other established methods of assessing skin perfusion [ 28, 29, 30, 31], and has been used to measure perfusion in hepatic [ 32] and colonic [ 33] tissue.