Words similar to single-copy
Example sentences for: single-copy
How can you use “single-copy” in a sentence? Here are some example sentences to help you improve your vocabulary:
Rather than one gene duplicate retaining the original function, while the other either degrades or evolves a new function, the original functions of the single-copy gene may be partitioned between the duplicates (subfunctionalization).
The structure of the scaffold is entirely consistent with previous 2Lh mapping studies in that the order of six single-copy sequences and the predicted Not I, Pme I, and Sfi I restriction maps of the scaffold (except for four regions corresponding to sequence gaps) are the same as those observed in the corresponding BAC contig and on genomic Southern blots.
It is informative to compare the epigenetic interactions of the 35S:GFP-COP1 transgenes with those of the PAI (trans)genes, the only other well-characterized system in Arabidopsis [ 12 ] . Both gene sets consist of relatively simple repeat structures and singlet loci, which reside in essentially single-copy environments of Arabidopsis ( [ 27 ] and unpublished observations).
The problem of random transgene integration can be overcome by targeting transgenes to a specific genomic locus by homologous recombination in ES cells [ 2 3 4 ] . A method that allows the introduction of single copy transgenes into the X-linked hprt locus has been described previously by Bronson et al [ 2 ] . In this approach single-copy transgenes are introduced 5' of the hprt locus by homologous recombination in ES cells.
Open reading frames (ORFs) in transposable elements can interfere with the identification of single-copy protein-coding genes, particularly when transposable elements are nested within introns.
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