Example sentences for: single-agent

How can you use “single-agent” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We identified 60 lung adenocarcinomas from individual patients with tumors shown to be sensitive or refractory to single-agent gefitinib or erlotinib and evaluated these tumors for mutations in EGFR and KRAS . Collectively, nine of 38 (24%) tumors refractory to either kinase inhibitor had KRAS mutations, while zero of 21 (0%) drug-sensitive tumors had such mutations ( p = 0.02) (Table 1).

  • Here, we show that mutations in KRAS are associated with primary resistance to single-agent gefitinib or erlotinib.


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