Example sentences for: simvastatin

How can you use “simvastatin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In cell culture, lovastatin and simvastatin decrease the release of Aβ by rat hippocampal neurons [12,14] while activating α-secretase-type ectodomain shedding [15,16].

  • Treatment with either atorvastatin, simvastatin, or PO alone increased sAPP α shedding, as expected.

  • Co-treatment of cells with PO plus either atorvastatin or simvastatin caused stimulation of sAPP α shedding to levels greater than the maximal levels of shedding achievable with inhibition of endocytosis using PO alone or with maximal doses of either statin alone ( p < 0.05).

  • Stock solution of simvastatin was prepared in ethanol and of simvastatin hydroxy acid in methanol-water (90:10) at 4°C.

  • Still, if the reported disease-modifying effect of atorvastatin is confirmed in the National Institute on Aging's large, multi-center trial of simvastatin, one or more compounds of this class may be among the first disease-modifying compounds approved by the Food and Drug Administration for slowing the progression of Alzheimer disease.


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