Example sentences for: siah

How can you use “siah” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The notion that Siah, a putative ubiquitin ligase, would have other roles in cell signaling is not surprising.

  • Therefore, a deletion mutant of Siah1a was constructed, GFP-Siah1a-CT, with the N-terminal RING-fmger domain deleted.

  • These results indicate that the presence of high levels of CaM can reverse the effect of Siah1a on calcium current modulation, presumably by competing for binding on the C-terminal tail of the receptor.

  • Coexpression of Siah1a caused a reduction in calcium current modulation to 12 ± 3%, as observed previously (n = 14).

  • These data also suggest that Siah1a is acting at the level of the receptor, since much of the calcium current modulation through group I mGluRs proceeds through a Gβγ-mediated pathway similar to that used by α 2 adrenergic receptors and mGluR2 [ 38 40 ] .


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