Words similar to shunt

Example sentences for: shunt

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It has been speculated that an abnormality of translocation of 3-MGC acid across the mitochondrial membrane may be the source of 3-MGC aciduria in these patients [ 23 ] . The link between 3-MGC aciduria and mitochondrial dysfunction may involve failure of mitochondrial uptake of 3-MGC acid or potentially defective ubiquinone biosynthesis leading to increased levels of mevalonate in the mevalonate shunt pathway with subsequent increased synthesis of 3-MGC acid [ 27 ] .
The pulmonary shunt fraction (Qsp/Qt) was calculated using the following equation [ 12]:
Because concentrations of 45 and 150 ppm were associated with a longlasting increase in blood methemoglobin concentration, which interfered with the calculation of venous and arterial O 2 content and pulmonary shunt, they were not included in the randomization, but were always administered as the last concentrations.
CI = cardiac index; PaO 2 = arterial oxygen tension; PVRI = pulmonary vascular resistance index; Qsp/Qt = shunt fraction; SVI = stroke volume index; SVRI = systemic vascular resistance index.
Although PEEP significantly improved shunt fraction, and consequently PaO 2 , its greater effect on cardiac output led to a reduction in DO 2 both at PEEP opt and PEEP max . However, none of the changes in haemodynamic parameters, including those in central venous pressure, pulmonary artery occlusion pressure, cardiac output, cardiac index and DO 2 , achieved statistical significance (Table 2and Fig.