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Stimulation through the BCR has been shown to induce changes in cell growth and viability in several B cell systems, including the human Daudi, chicken DT40 and mouse WEHI-231 and BCL 1 .3B3 B cell lymphomas [ 12 19 27 38 51 52 53 ] . For example, stimulation of BCL 1 .3B3 through the BCR suppressed exponential population growth in cell culture (Figure 1A).
Besides, as Goda and Weinberg have both shown at TomPaine.com, Hitler did plan for war with America.
For example, studies of the hairpin ribozyme have shown that data points can vary between individual experiments by as much as 50% [ 40 ] . Our data points typically varied from one another by less than 30%.
We then varied the pH from 7.0 to 8.5; E. coli RNAseH was active at all pHs, but no cleavage was found in reactions containing the permeabilized cores (data not shown).
As for Stx-cytotoxicity, none of the steroids, at any dose or exposure time, modified Gb3 content in any cell type (n = 3 each condition, data not shown).