Words similar to shh

Example sentences for: shh

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However, we did not detect NS expression of genes encoding Hh ligands like Shh (Figure 3B), similar to previous studies [19].
Generation of Ptc1 lacZ , Shh and Smo mutant mice has been described previously [ 25 26 ] . Ptc1 lacZ /+mice were kindly provided by Matthew Scott.
As expected, Ptc1 expression was not detected in the ventral neural tube of the vehicle-treated Shh -/-embryos (arrowhead, Figure 3g), whereas expression was seen in lateral plate mesoderm and weakly in somites (Figure 3g,k).
These data are reminiscent of prior studies demonstrating that excess endodermal Shh signaling disrupts pancreas development in vivo [16,34].
To test directly whether the absence of Hh signaling was required for expression of endodermal or islet markers, including FoxA3, Pdx1, and insulin, we added Shh protein to stage 4 cultures, which do not express Shh or genes encoding other Hh ligands like