Words similar to shh
Example sentences for: shh
How can you use “shh” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, we did not detect NS expression of genes encoding Hh ligands like Shh (Figure 3B), similar to previous studies [19].
This is most likely due to Ihh signaling in these tissues [ 26 ] . Both Shh and Ihh signaling were dependent on Smo, however, because Ptc1 expression could not be detected in Smo -/-embryos (Figure 3o).
Pregnant mice from Shh +/-and Smo +/-intercrosses were treated by oral gavage with vehicle or agonist (15 mg/kg) at 6.5 and 7.5 dpc.
The hedgehog ( hh ) gene was identified two decades ago in Drosophila as a critical regulator of cell-fate determination during embryogenesis [ 1 ] . Subsequent work in several model systems has defined and characterized the Hh gene family that encodes highly conserved secreted signaling proteins (for review see [ 2 ] ). Hedgehog (Hh) proteins are synthesized as approximately 45 kDa precursors that autoprocess in an unprecedented fashion, resulting in the covalent attachment of a cholesterol moiety to the amino-terminal half of the precursor [ 2 ] . This processed amino-terminal domain, Hh-Np, is responsible for the activation of a unique and complex signaling cascade that is essential for controlling cell fate throughout development and into adulthood [ 2 ] . In mammals there are three Hh-family proteins: Sonic (Shh), Indian (Ihh), and Desert (Dhh).
5) when the midline defects are first detectable in both Shh -/-and Smo -/-embryos, but prior to any general retardation of growth and development [ 26 27 ] . In both Shh +/-and Smo +/- Ptc1 lacZ /+embryos, Ptc1 was detected in ventral neural tube, somites and lateral plate mesoderm (Figure 3e,i,m).
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