Words similar to shh
Example sentences for: shh
How can you use “shh” in a sentence? Here are some example sentences to help you improve your vocabulary:
1 (NM_006168), NRSF/REST (U13879), Olig2 (NM_005806), Pdx1 (NM_000209), Ptc (U59464), RAR-α (NM_000964), RAR-β (BC060794), RAR-γ (NM_000966), Shh (L38518), Smo (AH007453), β-globin (NM_000518), and β-tubulin III (BC000748).
These data are reminiscent of prior studies demonstrating that excess endodermal Shh signaling disrupts pancreas development in vivo [16,34].
Following agonist treatment, we observed that the neural tube and somite expression of Ptc1 in Shh -/-embryos was greater than vehicle-treated wild-type levels (compare Figure 3h,lwith 3e,i).
To examine the effect of Sonic hedgehog (Shh) (R&D Systems), we added 300 nM mouse Shh in PBS every other day during stage 4. To quantify neurite outgrowths per cluster, 20 Shh-treated or control stage 4 IPC clusters were photographed under light microscopy, and digitized images were used to score neurites.
Furthermore, this supports the data showing that the agonist can activate signaling in Shh -/-embryos (Figure 3) and suggests that the agonist function is not only downstream of the Hh protein but also independent of the endogenous Hh-signaling modulators, Tout veloux and HIP, that act via the Hh ligand [ 2 ] . The competition experiment with forskolin showed identical inhibition curves for Hh protein and the agonist, strongly suggesting that the action of the small molecule is upstream of the protein-kinase-A-sensitive step in the pathway.
Loading...