Example sentences for: shedding

How can you use “shedding” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Why is APP a substrate for ectodomain shedding?

  • FACS analysis demonstrated that these cells were all apoptotic (not shown, see also [ 36 ] ). Although TGFβ1 acted anti-apoptotically in PP cultures (palmar and normal plantar fibroblasts) and prevented the shedding of cells into the media, its effect was dissimilar in non-PP cultures, where TGFβ1 had either no impact (keloid T and normal nonplantar fibroblasts) or was pro-apoptotic (keloid D cultures).

  • Transfection with the cDNA for a constitutively active (CA) ROCK1 molecule led to inhibition of statin-activated sAPP α shedding.

  • Treatment with either atorvastatin, simvastatin, or PO alone increased sAPP α shedding, as expected.

  • The additivity of statin- and PO-stimulated shedding is consistent with the hypothesis that statins act at or near the plasma membrane, prior to internalization of csAPP.


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