Words similar to sham-transfected
Example sentences for: sham-transfected
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7, DBD + 1-154) caused a statistically significant increase, relative to sham-transfected cells, in the proportion of cells in G1 (p << 0.01, n = 6).
No shift was observed with sham-transfected cells (not shown).
IL-6 given exogenously, since LNCaP cells do not produce IL-6, resulted in increased growth of the cells concomitant with activation of STAT3 [ 36 ] . LNCaP cells transfected with a plasmid conferring constitutive IL-6 expression demonstrated increased growth, relative to untransfected or sham-transfected cells [ 36 ] . However, other investigators have observed that IL-6 treatment of LNCaP cells reulted in terminal differentiation and inhibition of growth, associated with STAT3 activation [ 17 37 38 ] . The molecular basis for the apparent contradiction is unknown at this time.
The expression of C/EBPα-GFP or GFP-C/EBPα resulted in a statistically significant decrease in the amount of cells blocked in G2/M upon nocodazole treatment compared to sham-transfected cells (Fig.
05, n = 5) 9.66 +/- 6.08-fold higher promoter activity than did cells sham-transfected with the same expression vector deleted of the C/EBPα cDNA (Fig.