Example sentences for: seven-transmembrane

How can you use “seven-transmembrane” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The basic criteria for recognizing a particular OR gene as encoding a full-length, functional receptor candidate were the presence of an uninterrupted ORF starting with an ATG codon and a complete seven-transmembrane unit.

  • In this experiment, mRNAs from whole brains of mice of different genetic backgrounds which had been treated with an antagonist directed against the ligand-binding domain of a seven-transmembrane neuropeptide receptor [ 26] (the corticotropin-releasing hormone receptor 1 (CRH-R1) [ 27]) were compared to mRNAs from brains of mice lacking a functional CRH-R1 (CRH-R1 knockout mice [ 28]) using cDNA-microarrays (Table 1).

  • One such example is shown in Figure 1. The gene CG18314 encodes a G-protein-coupled receptor of the rhodopsin family, containing a seven-transmembrane protein domain with similarity to β 2 -adrenergic receptors of mouse and human [ 30, 31].

  • Wnt proteins have been shown to bind to Frizzleds (Fzs), which are seven-transmembrane receptors [ 5 6 ] . The binding of Wnts occurs within an aminoterminal cysteine-rich-domain (CRD) of Fzs.

  • Certain sequences underwent multiple recent duplications, resulting in large species specific sequence families, such as the C. elegans seven-transmembrane proteins acting as odorant and chemosensory receptors [ 19 20 ] . For query sequences belonging to such sequence families, orthologs (if present) are less effective for predicting specific information.


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