Example sentences for: self-splicing

How can you use “self-splicing” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In order to convert the Group I self-splicing intron to a regulatable aptazyme, it was necessary to first identify sequences or structures in the ribozyme whose conformation might modulate splicing activity.

  • The structural and kinetic properties of the Group I self-splicing intron from the thymidylate synthase ( td ) gene in bacteriophage T4 have been extensively studied.

  • Despite the chemical and physical differences between the E. coli cytoplasm and the environment in which the T. acidophilum intein is functioning in vivo, we found no indications that self-splicing of the intein was inefficient in E. coli.

  • These strategies should prove useful not only for self-splicing introns activated by drugs, but for introns activated by proteins or peptides.

  • However, four of the constructs, Th1P6, Th2P6, Th3P6, and Th1P5, showed good activity (>10% of wild-type) and increased self-splicing in the presence of theophylline.


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