Example sentences for: second-line

How can you use “second-line” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In Kenya, approximately 26,000 children die each year from malaria, or about 72 per day [ 9 ] . In August 1998 the Government of Kenya changed its first-line anti-malarial treatment from chloroquine to sulfadoxine-pyrimethamine (SP) [ 10 ] . Amodiaquine was to be the second-line drug.

  • Amodiaquine (AQ), the second-line drug, was the most frequently stocked (see Table 2).

  • Altogether, the authors conclude that the evidence base supports the first-line use of a tricyclic antidepressant for orally administered treatment of PHN, reserving the gabapentinoids for second-line use.

  • In the sixth report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI), peripheral alpha-1 antagonists are recommended not only as second-line anti-hypertensive therapy after low-dose diuretics and beta blockers, but also for specific indications such as therapy in men with hypertension and prostatism [ 2 ] . Alpha-1 antagonists represent effective therapy for prostatism, and fifty percent of men have histologic evidence of BPH by 60 years of age [ 3 4 ] . The National Ambulatory Medical Care Survey reported that the number of people on any type of peripheral alpha-1 antagonist in 1995 was approximately 6 to 7% of those with hypertension [ 5 ] . About 80% of surveyed physicians would choose these drugs as a first-line blood pressure agent for patients with hypertension and symptoms of BPH [ 6 ] .

  • C- myc -amplified patients affected by metastatic disease showed a tendency toward longer DFS with endocrine therapy, as compared with shorter DFS following second-line chemotherapy.


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