Words similar to seb

Example sentences for: seb

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To examine this, 6 h stimulation with SEB or CMV was carried out in peripheral blood cells of normal human CMV seropositive donors, in the presence or absence of anti-CD81 mAb 5A6, followed by intracellular staining for IL-2, IFNγ, or IL-4.
Other investigators have shown (in mouse systems) that commitment to Th1 or Th2 cytokine production by naïve T cells requires prior cell proliferation [ 24 ] ; and reversal of Th1 or Th2-committed cells requires at least several days of proliferation [ 25 ] . When normal human PBMC were stimulated for 7 days with SEB, the presence of 5A6 anti-CD81 mAb resulted in a modest increase in IL-4-producing T cells, when those cells were restimulated with PMA and ionomycin (Figure 4A).
The costimulatory effects were documented using two antigenic systems: a superantigen (SEB), and a conventional viral antigen (CMV).
For experiments examining cytokine production and CD69 induction, a "response region" was defined for CD69 +cytokine +cells using a positive control such as SEB stimulation, on a CD4-gated dot plot.
Similar results were seen when PBMC were stimulated with plate-bound anti-CD3 mAb, rather than SEB, for 7 days in the presence of 5A6 anti-CD81 mAb (Figure 4B).