Words similar to scid
Example sentences for: scid
How can you use “scid” in a sentence? Here are some example sentences to help you improve your vocabulary:
No suppression of development of PGIA in SCID mice was observed.
Under general anesthesia, 9- to 10-wk-old male NOD scid mice (purchased from Jackson Laboratories, Bar Harbor, Maine, United States) were engrafted with 1,000 handpicked IPC clusters in the right and left subcapsular renal space (500 IPC clusters each) or received a sham transplant of saline solution.
Spleen cells from arthritic animals, either depleted of CD25 +cells or without depletion, were injected into SCID mice together with proteoglycan.
First, CD4 +T cells selectively proliferate in response to proteoglycan antigens [ 14 ] . Second, prevention of arthritis can be achieved by in vivo treatment with anti-CD4 monoclonal antibodies [ 15 ] . Third, arthritis can be transferred to naïve BALB/c or severe combined immunodeficient (SCID) mice using T and B cells from arthritic animals [ 16 17 18 ] . Fourth, a proteoglycan-specific T-cell hybridoma (T-helper-1 type) can induce arthritis in BALB/c mice [ 19 ] . Finally, CD4 +T cells from arthritic animals are resistant to activation-induced cell death [ 20 ] . These data suggest a breakdown of peripheral tolerance and accumulation of autoreactive T cells in the periphery.
The transfers of CD4 +CD25 +T cells did not have any impact on incidence and severity of the disease in SCID mice as compared with transfer of CD4 +CD25 -T cells (Fig.