Example sentences for: scf

How can you use “scf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Size fractionation of total cell lysates prior to immunoprecipitation revealed co-elution of Pip1p with Pop1p, Pop2p, Pcu1p, and Psh1p in a high molecular weight complex of approximately 500 kDa, which we refer to as SCF Pop1p-Pop2p(Fig.

  • SCF Pop1p-Pop2pmediates polyubiquitylation of Rum1p in vitro

  • The failure of the Pop2p F-box to replace the F-box of Pop1p as well as the finding that it is not essential for Rum1p degradation could be explained, if it was not critically involved in SCF Pop1p-Pop2pprotein interactions.

  • For example, Cul1 mutations in mice result in the accumulation of the SCF substrate cyclin E but not of p27 another well characterized SCF substrate [ 32 ] . Among all of the substrates targeted for degradation by SCF in S. cerevisiae , it is the failure to degrade Sic1 that underlies the G1 arrest in cdc53 mutants [ 3 ] [ 4 ] . Thus, different substrates of the SCF appear to have particularly high dependence on SCF activity in different biological contexts.

  • Sequence coloring format (SCF) implementation


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