Example sentences for: sb-
How can you use “sb-” in a sentence? Here are some example sentences to help you improve your vocabulary:
The inhibitory effect of SB-203580 showed remarkable variation among the genes examined.
We observed that ets1 and ets2 transcript levels were slightly upregulated when cells were incubated with TGFβ and that this increase was partly inhibited by SB-203580.
However, pretreatment of the cells with 20 μM SB-203580 perturbed Smad3 nuclear accumulation, reducing the amount of Smad3 entering the nucleus and shifting the peak level of nuclear Smad3 to a later time point.
Interestingly, treating cells with TGFβ for 60 min yielded a similar amount of Smad3 in the nucleus, irrespective of whether SB-203580 was present or not.
Here we show that, in the highly invasive breast cancer cell line MDA-MB-231, the SB-202190 and SB-203580 inhibitors negatively altered Smad3 nuclear entry upon TGFβ stimulation.
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