Example sentences for: sb-

How can you use “sb-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These data suggest that SB-202190 and SB-203580 inhibit TGFβ-stimulated gene expression at least in part by downregulating transcription.

  • Using SB-203580, we found that not only was the total level of nuclear Smad3 in the presence of TGFβ reduced, but also that the nuclear entry of Smad3 was delayed and less prolonged.

  • Next, we studied the time-course of TGFβ-induced Smad3 nuclear entry in the presence or absence of SB-203580.

  • The inhibitory effect of SB-203580 showed remarkable variation among the genes examined.

  • We demonstrate that treatment of invasive MDA-MB-231 breast cancer cells with SB-202190 and SB-203580 interferes with TGFβ-induced Smad3 nuclear accumulation and that this is paralleled by a differential transcriptional response of TGFβ target genes.


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