Words similar to sb-

Example sentences for: sb-

How can you use “sb-” in a sentence? Here are some example sentences to help you improve your vocabulary:

However, pretreatment of the cells with 20 μM SB-203580 perturbed Smad3 nuclear accumulation, reducing the amount of Smad3 entering the nucleus and shifting the peak level of nuclear Smad3 to a later time point.
SB-202190 and SB-203580 downregulate transcription from TGFβ-responsive genes
We have previously demonstrated that TGFβ upregulates PTHrP and PAI-1 RNA levels in MDA-MB-231 cells [ 19 ] . TGFβ affected PTHrP expression primarily by increasing the level of the promoter P3-specific transcript [ 19 ] . Quantitative PCR analysis using primers allowing the detection of PTHrP P3 and PAI-1 transcripts indicated that incubation of MDA-MB-231 cells with SB-202190 and SB-203580 greatly inhibited TGFβ-induced increase in PTHrP and, to a lesser extent, PAI-1 mRNA levels (Fig.
The inhibitors PD-98059, Y-27632, SB-202190 and SB-203580 were obtained from Calbiochem and dissolved in dimethyl sulfoxide.
Interestingly, treating cells with TGFβ for 60 min yielded a similar amount of Smad3 in the nucleus, irrespective of whether SB-203580 was present or not.