Example sentences for: sb-

How can you use “sb-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The inhibitory effect of SB-203580 showed remarkable variation among the genes examined.

  • We observed that ets1 and ets2 transcript levels were slightly upregulated when cells were incubated with TGFβ and that this increase was partly inhibited by SB-203580.

  • However, pretreatment of the cells with 20 μM SB-203580 perturbed Smad3 nuclear accumulation, reducing the amount of Smad3 entering the nucleus and shifting the peak level of nuclear Smad3 to a later time point.

  • Interestingly, treating cells with TGFβ for 60 min yielded a similar amount of Smad3 in the nucleus, irrespective of whether SB-203580 was present or not.

  • Here we show that, in the highly invasive breast cancer cell line MDA-MB-231, the SB-202190 and SB-203580 inhibitors negatively altered Smad3 nuclear entry upon TGFβ stimulation.


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