Example sentences for: sb-
How can you use “sb-” in a sentence? Here are some example sentences to help you improve your vocabulary:
These data suggest that SB-202190 and SB-203580 inhibit TGFβ-stimulated gene expression at least in part by downregulating transcription.
Using SB-203580, we found that not only was the total level of nuclear Smad3 in the presence of TGFβ reduced, but also that the nuclear entry of Smad3 was delayed and less prolonged.
Next, we studied the time-course of TGFβ-induced Smad3 nuclear entry in the presence or absence of SB-203580.
The inhibitory effect of SB-203580 showed remarkable variation among the genes examined.
We demonstrate that treatment of invasive MDA-MB-231 breast cancer cells with SB-202190 and SB-203580 interferes with TGFβ-induced Smad3 nuclear accumulation and that this is paralleled by a differential transcriptional response of TGFβ target genes.
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