Words similar to sapp
Example sentences for: sapp
How can you use “sapp” in a sentence? Here are some example sentences to help you improve your vocabulary:
Unlike sAPP α , which is generated at the plasma membrane, most sAPP β is probably generated by cleavage within the trans -Golgi network and endocytic pathway vesicles.
Monoclonal antibody 6E10 against residues 1–16 of human Aβ (Signet, Dedham, Massachusetts, United States) was used to detect human holoAPP or sAPP α . Anti-ROCK1 antibody was purchased from Chemicon (Temecula, California, United States).
Based on these reports, we asked whether the Rho/ROCK pathway might play a role in controlling shedding of sAPP α following statin application.
Co-treatment of cells with PO plus either atorvastatin or simvastatin caused stimulation of sAPP α shedding to levels greater than the maximal levels of shedding achievable with inhibition of endocytosis using PO alone or with maximal doses of either statin alone ( p < 0.05).
Low doses (<1 μM) of mevalonic acid did not affect statin-induced sAPP α shedding, but complete inhibition of statin-activated sAPP α shedding was achieved with higher doses of mevalonic acid (100 μM).
Loading...