Example sentences for: sapp

How can you use “sapp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Based on this series of results, we concluded that both basal and activated sAPP α shedding from cultured cells are controlled by ROCK activity.

  • Cells and media were harvested, and levels of sAPP α , holoAPP, and csAPP were measured.

  • A popular model holds that sAPP α may function as a neurotrophic and/or neuroprotective factor, and may promote neurite outgrowth [52].

  • Treatment of cells with a farnesyl transferase inhibitor or expression of a dominant negative (DN) ROCK1 molecule led to enhanced sAPP α shedding, supporting the notion that shedding is modulated by the isoprenoid pathway.

  • FTI-1 increased the shedding of sAPP α , but the combination of a statin plus FTI-1 increased sAPP α shedding to levels greater than those achievable by using either compound alone (Figure 3; p < 0.05).


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