Words similar to sapp

Example sentences for: sapp

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Taken together, these results suggest the existence of a reciprocal relationship between isoprenoid-mediated Rho/ROCK signaling and sAPP α shedding, i.e., activation of ROCK1 blocks basal and stimulated shedding while ROCK1 inhibition apparently relieves a tonic negative influence exerted on shedding by ROCK1 activity.
Fold increases in released sAPP α in the same experiments were approximately 3- to 4-fold (2.
Unlike sAPP α , which is generated at the plasma membrane, most sAPP β is probably generated by cleavage within the trans -Golgi network and endocytic pathway vesicles.
HoloAPP levels are likely limiting at one or more sorting steps in the late secretory pathway, since activated sAPP α shedding is apparently accompanied by diminished generation of sAPP β [51].
When CA ROCK1 was introduced, however, shedding of sAPP α from both untreated and simvastatin-treated cells was diminished (Figure 5; p < 0.05 versus GFP control).