Words similar to sapp

Example sentences for: sapp

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Co-treatment of cells with PO plus either atorvastatin or simvastatin caused stimulation of sAPP α shedding to levels greater than the maximal levels of shedding achievable with inhibition of endocytosis using PO alone or with maximal doses of either statin alone ( p < 0.05).
Fold increases in released sAPP α in the same experiments were approximately 3- to 4-fold (2.
Low doses (<1 μM) of mevalonic acid did not affect statin-induced sAPP α shedding, but complete inhibition of statin-activated sAPP α shedding was achieved with higher doses of mevalonic acid (100 μM).
Based on this series of results, we concluded that both basal and activated sAPP α shedding from cultured cells are controlled by ROCK activity.
Unlike sAPP α , which is generated at the plasma membrane, most sAPP β is probably generated by cleavage within the trans -Golgi network and endocytic pathway vesicles.