Words similar to sandwich-barrel

Example sentences for: sandwich-barrel

How can you use “sandwich-barrel” in a sentence? Here are some example sentences to help you improve your vocabulary:

Evidence is presented that the ultimate ancestor of RNA polymerases might have been a RNA-binding DPBB domain, which functioned as a cofactor for a polymerase ribozyme, and that subsequent evolution of DDRPs and RDRPs proceeded via accretion of various simple modules, such as the sandwich-barrel hybrid motif domain, around this conserved core.
Visual examination of the structure of this insert domain revealed a topology with elements of both a sandwich and a barrel, and two "waist"-like structures that are characteristic of the sandwich-barrel hybrid motif (SBHM) fold [ 75 76 ] (see also the SCOP database [ 65 ] ). The SBHM fold is present in biotin/lipoate carrier domains and their homologs found in a variety of enzymes and transporters [ 76 ] . A DALI search with this insert domain from the β subunit of Thermus DDRP showed similarity to the SBHMs from various biotin/lipoate-binding enzymes, such as acetyl-CoA carboxylase (1bdo) or dihydrolipoamide acetyltransferase (1iyu) with Z scores of ~6 and RMSD ~2.