Words similar to salt-sensitive
Example sentences for: salt-sensitive
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The inbred Dahl/Rapp rat is a genetic model of salt-sensitive hypertension [ 3 4 ] . On a diet containing 8.0% NaCl, young Dahl/Rapp salt-sensitive (S) rats rapidly and uniformly manifest low-renin hypertension and die from hypertensive nephrosclerosis within weeks of institution of the high-salt diet [ 5 ] . The pathology is identical to human hypertensive renal disease and consists of arteriolosclerosis, glomerulosclerosis, and interstitial scarring with tubular cell dropout.
Studies were conducted using 40 male Dahl/Rapp salt-sensitive (SS/Jr, termed S) and 40 male Sprague-Dawley (SD) rats, initially 28 days of age, obtained from Harlan Sprague Dawley, Indianapolis, IN.
Recent evidence suggests that apoptosis is involved in several pathological processes in the lung [ 30 31 32 ] and kidney [ 33 34 35 36 37 ] . Using the Dahl/Rapp salt-sensitive (S) rat, which develops hypertensive nephrosclerosis that resembles the human disease process [ 5 ] , this laboratory demonstrated an early and inappropriate apoptotic process that occurred in both glomerular and tubular compartments of the kidneys and correlated with the decline in glomerular filtration rate.
S, Dahl/Rapp salt-sensitive rat