Example sentences for: saha

How can you use “saha” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Histones were isolated and lyophilized from nuclear extracts in SAHA treated and untreated TM10 and TM2H cell lines following a protocol described earlier [ 26].

  • We identified a novel mechanism for SAHA in cell growth arrest through inhibition in DNA synthesis, concomitant with significant increases in the nuclear localization of pRb-2/p130 associated with E2F-4, decreases in key molecules in DNA synthesis (E2F-1, PCNA and p21), and increases in histone H3 and H4 protein and acetylation levels.

  • Bercsi S, Brickner P, Saha D. Alcohol use and abuse in the frail, homebound elderly: a clinical analysis of 103 persons.

  • It is plausible to suggest that the inhibition in E2F-1 protein levels by SAHA was either at the transcription level or induction of the ubiquitin-protein ligase responsible for E2F-1 degradation, but not E2F-4, and this resulted in blocked DNA synthesis.

  • The inhibition in nuclear p21 in SAHA treated TM2H as well as TM10 cells underscores that SAHA-arrested cell growth is through a p53-independent pathway.


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