Words similar to sα
Example sentences for: sα
How can you use “sα” in a sentence? Here are some example sentences to help you improve your vocabulary:
First, others have shown that in COS-7 cells endogenous sα i2 is not detected at PM but only found intracellularly [ 3 4 ] , although one cannot rule out that a small but functionally significant fraction of sα i2 reaches the PM.
Thus, it is more likely that indeed sα i2 is deficient in binding to βγ, but this effect is a consequence of its instability.
sα i2 may exist in a state that does not interact well with βγ simply because it is in the process of being irreversibly inactivated [ 9 10 ] . Similarly, α i2 A327S appears not to be defective in its intrinsic ability to interact βγ [ 10 ] , and co-expression of βγ shifts α i2 A327S, like sα i2 , from intracellular to plasma membranes (Figure 8).
Thus, the following experiments concentrated on addressing the alternative hypothesis: sα i2 is unstable and rapidly degraded due to disruptions in the C-terminus, and such instability results in a failure of sα i2 to reach its proper place at the PM.
Consistent with this idea, sα i2 was refractory to stable expression even though cells stably expressing α i2 were easily selected (not shown).
Loading...