Example sentences for: rpa

How can you use “rpa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Five μg of total RNA was hybridized to the in vitro transcribed hAPO-4 probe set (PharMingen, SanDiego, CA), and the RPA assay was performed according to the manufacturer's protocol.

  • Deletion of this acidic cluster of BLM has an effect on localization and SCE frequency and may target BLM to RPA bound to single-stranded DNA, or it may allow BLM to function with chromatin remodeling complexes at sites of ectopic invasion events.

  • Ribonuclease protection assay (RPA)

  • These target proteins include the c-Abl tyrosine kinase, the p53 tumor suppressor, the Chk1 and Chk2 serine/threoine kinase, the p34 subunit of replication protein A (RPA), Chk1 serine/threoine kinase and NBS1 kinase which is mutated in human autosomal recessive disease Nijmegan breakage syndrome [ 16 17 18 19 20 21 22 23 ] . Clinical characteristics of AT patients include hypersensitivity to irradiation, thymic dysplasia, immune defects and higher tendency to develop malignant tumor, suggesting that ATM function is critical in DNA damage repair and tumor suppression.

  • Sample RNA (20μg total RNA) was coprecipitated with the BRCA1 probe and the cyclophilin control probe [ 32], resuspended in Hyb-speed RPA (Ambion) hybridization buffer at 95°C, and then incubated at 68°C for 10min.


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