Words similar to roscovitine
Example sentences for: roscovitine
How can you use “roscovitine” in a sentence? Here are some example sentences to help you improve your vocabulary:
We determined whether the inhibition of transcription is specific to flavopiridol by comparing gene expression profiles of flavopiridol-treated cells with those of cells treated with the CDK inhibitors roscovitine and 9-nitropaullone.
9-nitropaullone, the most potent member of a novel class of the paullone CDK inhibitor family, inhibits CDK1/cyclin B at 10-fold lower concentrations than flavopiridol and roscovitine [ 22, 23, 24].
Roscovitine is a purine derivative that inhibits CDK1, CDK2 and CDK5 and blocks cell-cycle progression both in late G1/early S and in M phase [ 18, 19, 20, 21].
Actinomycin D, roscovitine, phorbol ester and lipopolysaccharide (LPS) were purchased from Calbiochem.
As shown in Figure 1c, the gene expression changes caused by roscovitine and 9-nitropaullone were different from those of flavopiridol, and only flavopiridol globally reduced mRNA levels.