Words similar to rofecoxib
Example sentences for: rofecoxib
How can you use “rofecoxib” in a sentence? Here are some example sentences to help you improve your vocabulary:
The amount of information (number of patients randomized) was insufficient to make any authoritative statement about adverse events, or compare the adverse event profile of rofecoxib 50 mg in single doses with other single dose analgesics.
Trials tried to discourage remedication within 90 minutes, and two patients in one trial were excluded because they remedicated within 90 minutes, one on placebo and one on rofecoxib 50 mg [ 26 ] . This was not reported consistently ( Additional File 3).
The efficacy of rofecoxib in these five classical clinical analgesic assays is in contrast to two randomized comparisons of rofecoxib with placebo when given before the operation in adults [ 36 ] and children [ 37 ] . The methodological difficulties and lack of effect of preemptive analgesia have been pointed out previously [ 38 39 ] . In these two trials additional difficulties were the large between-individual variation in morphine consumption in adults [ 36 ] , and the use of a novel (unlicensed) syrup formulation of rofecoxib in children [ 37 ] . Lack of a demonstrable analgesic effect in preemptive studies does not negate a substantial postoperative effect when patients both have pain and can swallow.
QUORUM guidelines were followed [ 12 ] . Possible studies for inclusion were sought through searching the Cochrane Library (issue 4, 2001), Biological Abstracts (March 2002), MEDLINE (March 2002) and PubMed (March 2002) using rofecoxib as a free text term.
In three trials information on patients suffering nausea and vomiting was available, showing that these adverse events occurred less frequently with rofecoxib 50 mg than placebo.
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