Words similar to rofecoxib
Example sentences for: rofecoxib
How can you use “rofecoxib” in a sentence? Here are some example sentences to help you improve your vocabulary:
One of them was David Graham, Associate Director in the United States Food and Drug Administration's (FDA's) Office of Drug Safety, whose research on rofecoxib (Vioxx) pointed to the serious cardiovascular risks of the drug [1].
The pain models, third molar dental extraction and orthopaedic surgery, are commonly used in research and choice of model does not appear to influence results in single-dose analgesic studies when patients are able to take oral medication [ 13 ] . Comparison of rofecoxib 50 mg with other analgesics over six hours is legitimate, because the same outcome was measured in the same way in the same patients over the same period of time, and with same comparator.
Two trials had information on any patient with any adverse event (Table 1), with no difference between rofecoxib 50 mg and placebo.
In three trials information on patients suffering nausea and vomiting was available, showing that these adverse events occurred less frequently with rofecoxib 50 mg than placebo.
The amount of information (number of patients randomized) was insufficient to make any authoritative statement about adverse events, or compare the adverse event profile of rofecoxib 50 mg in single doses with other single dose analgesics.