Example sentences for: rnai

How can you use “rnai” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Moreover, RNAi will permit the ablation of essential gene products, at any time point in infection, or on a desired parasitic stage following synchronization.

  • The discovery of RNAi established a requirement for dsRNA in silencing, but details of the mechanism remained unclear.

  • Conditional RNAi should be particularly useful to study phenotypes in the adult such as aging and lifespan.

  • The following files are available as additional data: a complete listing of gene ontology mappings for M. incognita clusters organized into (a) biological process, (b) cellular component, (c) molecular function (Additional data file 1); complete KEGG biochemical pathway mappings for M. incognita clusters (Additional data file 2); a complete list of C. elegans RNAi phenotypes for genes with M. incognita homologs (Additional data file 3); classification by RNAi phenotype of C. elegans genes with M. incognita homologs (Additional data file 4).

  • RNA interference (RNAi), mediated by short interfering double-stranded RNA molecules (siRNA or dsRNA), is now recognized as a major mechanism of post-transcriptional gene silencing (PTGS) in essentially all eukaryotes [ 16 ] . Recently, the technique has been successfully applied to cultured mammalian cells, whereby introduction of 21-nucleotide long synthetic dsRNA molecules corresponding to specific mRNA sequences effectively and specifically degraded the cognate mRNAs and abrogated the expression of the corresponding proteins [ 17 18 ] . This prompted us to test a similar approach to knockdown PfPP1 function in the erythrocytic P. falciparum stages.


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