Example sentences for: rna-mediated

How can you use “rna-mediated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The central player in RNA-mediated gene silencing is a double-stranded RNA (dsRNA) that is chopped into tiny RNAs by the enzyme Dicer.

  • Interestingly, perfect or near-perfect target complementarity is associated with mRNA degradation [ 24 25 26 ] , similar to the effects of siRNA, whereas imperfect base-pairing is associated with regulation by translational inhibition [ 6 27 ] . Recently, siRNAs with imperfect match to target mRNA were observed to function as translational inhibitors [ 28 ] , suggesting that the type of 21-22 nucleotide RNA-mediated regulation may be largely determined by the quality of target complementarity.

  • Although the mechanistic details are still under investigation, RNA-mediated silencing has already provided a powerful tool for studying gene function and spawned a fledgling industry that aims to develop novel RNA-based therapeutics to treat human diseases (Robinson 2004).

  • Plant scientists have figured prominently in RNA-mediated silencing research.

  • Although the word ‘revolution’ should not be used lightly in science, there is no other way to describe the recent explosion in our awareness and understanding of RNA-mediated gene silencing pathways.


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