Example sentences for: risperidone

How can you use “risperidone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, risperidone had no significant effect on the EMG during phase 1 (Fig 6A).

  • We undertook this study to examine the effects of olanzapine and risperidone on the cystometrogram of anesthetized rats.

  • Clozapine is a widely used atypical neuroleptic with affinity for multiple receptors, including dopamine, serotonin, alpha adrenergic, muscarinic and histaminergic receptors [ 1 2 ] . Although clozapine is effective in the treatment of schizophrenia refractory to traditional antipsychotic medication, it also has a number of significant side effects ranging from the potentially fatal but rare agranulocytosis to weight gain, constipation, seizures and urinary incontinence [ 3 ] . Urinary problems have been reported in the clinical literature with incontinence present in up to 44% of patients [ 4 ] and enuresis in 27% of patients [ 5 ] . Since clozapine has potent anti-muscarinic and anti-alpha adrenergic effects [ 2 ] , it has been proposed that peripheral effects on the lower urinary tract might be responsible for the micturition disturbances [ 6 ] . Incontinence has also been reported following therapy with other atypical neuroleptics such as risperidone [ 7 8 9 ] and recently, olanzapine [ 10 ] .

  • Selective antagonism of D2 receptors only modestly reduced the amplitude of HFO without affecting any other urodynamic parameters [ 6 35 ] . Therefore, it is possible that olanzapine and risperidone decrease the amplitude of the HFO, at least partly, through antagonism of D2 receptors.

  • At 10 mg/kg of risperidone, the phase 2 EMG was 71 (± 22) % and was not significantly different from vehicle.


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