Words similar to rhodopsin
Example sentences for: rhodopsin
How can you use “rhodopsin” in a sentence? Here are some example sentences to help you improve your vocabulary:
We found that photoreceptor-specific genes typically showing high, retina-specific expression that began around one week after birth, coinciding exactly with the previously reported increase in expression of rhodopsin and other rod-specific genes [ 13 14 15 ] . We typically saw higher expression of photoreceptor-specific genes in microSAGE libraries made from microdissected outer nuclear layer (97% rods versus 70% rods for whole retina) and, in many cases, higher expression in P10.
Expression of an attenuated diphtheria toxin gene under the control of rhodopsin promoter results in the specific elimination of rod photoreceptors in the retina [ 34].
For example the cone rod homeobox (Crx) binds and transactivates the rhodopsin promoter [ 26 ] . However, it has not been determined whether other rhodopsin GPCRs are also regulated by homeobox proteins.
This GPCR-mediated regulation of ion channels also depends on the coordination and parallel regulation of protein tyrosine kinase and protein tyrosine phosphatase activities [ 24 ] . GPCRs can also interact with the growing family of PDZ domain-containing proteins [ 25 ] . All of these relationships are reflected in our study by the strong correlation between 7 transmembrane receptors (rhodopsin family) (PF00001), protein kinases (PF00069), protein tyrosine phosphatases (PF00102), ion transport proteins (PF00520), and PDZ domain proteins (PF00595).
For example, levels of 4-HNE increased significantly in the vitreous of patients with proliferative vitreoretinopathy compared with controls [ 17 ] . Further, 4-HNE forms a stable adduct with rhodopsin in the photoreceptor, which may interfere with its functions [ 18 ] . 4-HNE even causes cataracts in cultured rat lens [ 19 20 ] . Whether oxidative stress on RPE can cause accumulation of cellular HNE-protein adducts remains unknown.
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