Words similar to rhoa

Example sentences for: rhoa

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Electroporation of polyclonal antibodies specific for RhoA mimicked the C3 induced phenotype (data not shown).
Western blotting analysis confirmed the presence of RhoA (~25 kDa) in the human T cell lines HPB-ALL and CEM (Figure 1A).
ADP-ribosylation of Rho proteins by C3 exoenzyme prevents neurite retraction in the specialized growth cone of developing neurons, and in fact promotes neurite outgrowth in the same fashion as microinjection of purified dominant negative RhoA T19N [ 39 ] . In these instances, neuronal N1E-115 cell outgrowth induced by inactivation of RhoA was mimicked by microinjection of Rac1- or Cdc42-GST fusion proteins, and could be abolished by coinjection of dominant negative Cdc42 T17Nor Rac1 T17N [ 39 ] . From these results, the authors concluded that inactivation of RhoA by C3 exoenzyme treatment resulted in the activation of Rac1 and Cdc42 GTPases, suggesting the mutually exclusive function of RhoA and Rac1/Cdc42.
Although ADP-ribosylation of Rho does not significantly alter the subcellular distribution of RhoA, Rho activity is inhibited.
Immunolocalization studies of RhoA in C3 treated HBP-ALL cells spreading on fibronectin showed no gross differences in RhoA distribution, however clusters of RhoA were more delineated along the finger-like dendritic processes of the C3 treated cells.