Words similar to rhinovirus
Example sentences for: rhinovirus
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Our limit of detection for the collection, extraction and amplification of aerosolized rhinovirus was 1.3 TCID 50 . The spiking experiments we conducted had a limit of detection of approximately 0.8 TCID 50 or 60% of what was detected when the virus was aerosolized.
A cationic phthalocyanine was reported to inhibit human rhinovirus type 5 (RV-5) infection [ 21 ] . Selected porphyrin derivatives inhibit specific viral targets including retroviral reverse transcriptase [ 22 23 24 25 26 ] and HIV-1 protease [ 27 ] .
These techniques allow for a highly sensitive method to conduct air sampling for rhinovirus.
Although rhinoviruses have been thought to be transmitted via large droplets or contact [ 7 ] , studies in the 1980's demonstrated that fomites are not an effective means of transmitting rhinovirus infections [ 8 9 10 ] . While direct inoculation of respiratory secretions has been shown to transmit infection, this is not a likely route of transmission in older children and adults as survival on hands is brief [ 9 ] . Airborne transmission of infection was clearly demonstrated in one experimental study on adults [ 8 ] . However, in the absence of epidemiological studies designed to conclusively identify modes of transmission, the role of airborne transmission in viral respiratory infection remains controversial.
Rhinoviruses have been associated with 40% to 65% of "common colds" studied by methods of virus culture [ 1 2 ] . With the use of reverse transcriptase - polymerase chain reaction (RT-PCR), rhinovirus has been shown to be associated with 53% of all colds throughout the year and up to 92% of colds during the autumn outbreak period [ 3 ] . Rhinviruses have been implicated in the exacerbation of asthma symptoms [ 4 ] and may even play a role in asthma related deaths [ 5 ] . Due to their role in the exacerbation of asthma symptoms, rhinoviruses are a major cause of pediatric hospitalizations [ 6 ] .
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