Words similar to rheumatoid
Example sentences for: rheumatoid
How can you use “rheumatoid” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thus, it is interesting to speculate that IL-2 and IL-4 are downregulated in the rheumatoid synovium by some active repressor mechanism induced by the synovial microenvironment.
Heparinized venous blood, synovial fluid, and synovial tissue were obtained from patients who fulfilled the American College of Rheumatology criteria for the diagnosis of rheumatoid arthritis [ 27].
Given that TGF-β1 is able to induce new matrix synthesis from chondrocytes in culture as well as able to block inflammation in vivo , it has been proposed that local intra-articular gene transfer of TGF-β1 could be therapeutic for the treatment of rheumatoid arthritis as well as osteoarthritis.
Moreover, anti-TNF-α treatment resulted in a modest inhibition of murine IL-1β production in the diseased joint, which is consistent with previous findings that anti-TNF-α antibody inhibits the generation of IL-1 in collagen-induced arthritis and IL-1, IL-6, and IL-8 in rheumatoid synovial cultures [ 26 27 ] . Our study provides preclinical evidence supporting the use of anti-TNF-α mAb in ameliorating arthritic pathology.
It is logical to infer that the increased susceptibility of aged individuals to rheumatoid arthritis and other autoimmune pathologies, may be due to increased TNF-α (and IFN-γ) production by the CD8 +CD28 -T cell.