Words similar to rgs

Example sentences for: rgs

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For instance, RGS4 and RGS-GAIP [ 11 ] , RGS3 [ 9 ] , RGS2 [ 46 ] , and RGS7 (our unpublished findings) all bind Gqα, the established G protein that transduces GnRH receptor signaling [ 38 ] . Nevertheless, RGS2 and 4 [ 9 ] , and RGS-GAIP and RGS7 (our unpublished data) are weak or null inhibitors of GnRH receptor signaling.
The proper orientation of the RGS3 cDNA was confirmed by nucleotide sequencing.
The results of the current investigation as well as those presented earlier [ 31 ] nominate two molecular mechanisms as playing roles in setting the responsiveness level of GnRH receptor signaling; i.e., the RGS3 system acts at the G protein transducing step and the GRK/β arrestin system acts at the level of the receptor.
cDNAs representing the GnRH receptor and RGS3 or RGS3T were co-transfected into COS-1 cells for GnRH-A treatment 72 h later; intracellular IP 3 concentrations were measured at 0, 10, 20, and 30 sec after addition of 10 -7M GnRH-A (Fig.
The findings of the current, and an earlier study [ 9 ] , demonstrate clearly that RGS3 suppresses GnRH receptor signaling in a heterologous cell system.