Example sentences for: rgc

How can you use “rgc” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Strikingly, all old AKXD28 mice have severe retinal ganglion cell loss typically associated with severe optic nerve excavation, whereas, few old D2 mice have severe RGC loss and optic nerve excavation is rarely, if ever severe (defined here as extending to a level out side of the inner nuclear layer).

  • Paralleling RGC loss, optic nerve head excavation or cupping was also more severe and more frequent (P < 0.0001, Chi-square) in AKXD28 than D2 mice.

  • Mice at 18 or 19 months had no more than a moderate loss of RGCs, and only 1 of 11 mice older than 20 months had severe RGC loss.

  • Vitreous glutamate levels increase when IOP is elevated in various species and this increase is associated with RGC death [ 24, 25, 26].

  • Acting through N-methyl-D-aspartate receptors, glutamate is believed to be a potent initiator of RGC neurotoxicity [ 26] and, as described here, the vitreous of at least some AKXD28 mice contains elevated glutamate concentrations when IOP is elevated.


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