Example sentences for: retrograde

How can you use “retrograde” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Our data suggest a mechanism of de-localization of Arp3 consistent with dissociation or diffusion rather than retrograde flow.

  • And the inside WP piece dwells mostly on the absence of a clear explanation for these decreases, while also noting two retrograde movements: There hasn't been a significant crime drop among white suburban and rural teen-agers, and cities between 10,000 and 24,999 have experienced a murder increase.

  • In the carotid arteries, the system works by occluding the common carotid, which creates a negative pressure gradient distal to the balloon occlusion and establishes retrograde flow in the internal carotid artery.

  • Current understanding of the retrograde flow of actin has been influenced by the use of BDM in the sea urchin coelomocyte and Aplysia bag cell neuron systems.

  • Rab proteins comprise a large family of Ras-related GTPases that function in the anterograde and retrograde trafficking of proteins in mammalian cells [ 1 2 3 ] . Different Rab proteins reside in specific subcellular membranes or organelles, where they mediate vesicular transport between discrete donor and acceptor compartments in the endocytic or exocytic pathways [ 4 5 ] . Detailed studies of a few Rab proteins ( e.g .; Rab1, Rab5 and Rab9) have led to a general model wherein Rab proteins are presumed to cycle on and off donor and acceptor membranes in connection with changes in their guanine nucleotide state [ 6 7 8 ] . In the active GTP-bound state, Rab proteins associate with budding transport vesicles [ 9 10 11 ] and appear to participate in the assembly of membrane docking complexes [ 12 13 14 ] . Following vesicle fusion with the acceptor compartment and GTP hydrolysis, the inactive GDP-bound Rab is extracted from the membrane by a carrier protein termed guanine nucleotide dissociation inhibitor (GDI) [ 15 16 17 ] . The GTPase can then re-enter the transport cycle through nucleotide exchange promoted by a specific exchange factor at the donor vesicle membrane [ 18 19 20 ] . In addition to changes in guanine nucleotide state, the posttranslational prenylation of Rab proteins plays an important role in the cycling mechanism.


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