Words similar to reticulum
Example sentences for: reticulum
How can you use “reticulum” in a sentence? Here are some example sentences to help you improve your vocabulary:
At the end of the perfusion protocol, maximal fluorescence, used in the calculation of [Ca 2+]i was determined by tetanizing the heart with a bolus of calcium chloride (20 mM) without any energy substrate, and with cyclopiazonic acid (Sigma Chemical Co., 10 μM), which is a potent inhibitor of Ca 2+-ATPase and thus blocks calcium uptake by the sarcoplasmic reticulum [ 28 ] . Fluorescence and pressure were monitored continuously, and the point of maximal fluorescence was taken as the point were pressure stabilized at a steady state.
In contrast, sα i2 was not detected at plasma membranes, but instead typically displayed an intracellular and perinuclear staining pattern (Figure 2Band 2D), consistent with localization to intracellular membranes as previously described [ 3 4 ] . The subcellular localization of sα i2 showed overlap in immunofluorescent staining with the Golgi protein, β-COP (Figure 3Aand 3B) and the endoplasmic reticulum protein PDI (Figure 3Cand 3D); localization of sα i2 exclusively to Golgi was not observed, even at the lowest levels of detection.
The resulting enzyme is both mislocalized and unstable [ 27 ] . Another mutation, Q1098P, was found to cause retention of SI in the transport pathway between the endoplasmic reticulum and Golgi apparatus [ 28 ] . An unusual mutation, Q117R, that alters the structure close to the O-glycosylated stalk domain, leads to random distribution of the enzyme to both the apical and basolateral cell membranes [ 29 ] . An unusual human mutation that causes SI to be secreted rather than retained in the plasma membrane demonstrates that the enzyme is required to be at the enterocyte cell surface [ 30 ] .
The nuclear chromatin, abundant mitochondria, reticulum and coated vesicles, had normal appearance.
An illustration is provided by the gene KAR2 , which encodes an HSP70 protein-folding chaperone localized to the endo-plasmic reticulum (ER) that is known to respond to defects in ER secretion and to unfolded proteins in this organelle (see [ 23] for review).
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