Words similar to resuppression
Example sentences for: resuppression
How can you use “resuppression” in a sentence? Here are some example sentences to help you improve your vocabulary:
Phase II procedures for both arms included the following: (1) monitoring for patient study withdrawal criteria as described in phase I, (2) determining time to primary end point of a viral load greater than 5,000 copies/ml, (3) monitoring until the time of therapy reinitiation at a viral load greater than 30,000 copies/ml for three consecutive time points, and (4) after reinitiation of therapy, follow-up on therapy to confirm resuppression to less than 50 copies/ml at 6, 10, and 14 wk on therapy.
However, based on the lack of association between viral resistance detected off-drug shortly after TI and resuppression by the same regimen in all patients, it remains undetermined to what extent TIs favor the detection of archived mutations in chronically suppressed patients and to what extent these mutations are a signal for a future therapy failure.
In contrast, our strategy mandated resuppression of viral replication to less than 50 copies/ml before each TI and presents the first comparison of viral replication during a final open-ended interruption of therapy between patients randomized to complete three sequential TIs or stay under continuous therapy.
In spite of fluctuations in CD4 T cell count levels between the start and end of each monitored TI, a recovery of CD4 count levels was achieved upon resuppression following each TI in conjunction with a retention of lymphoproliferative responses against
when measured between arms before the open-ended TI (see Figure 4), nor following resuppression after monitored TI reinitiation cycles in the repeated interruptions arm (see Figure 5).
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