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Example sentences for: resulted
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Such constructs have been used successfully to define the functions of Rab1A and Rab1B [ 26 27 28 ] , Rab4 [ 29 ] , Rab5 [ 30 31 ] and Rab6 [ 32 ] . Unexpectedly, we found that expression of the mutant forms of Rab24 in cultured cells resulted in their accumulation in a striking array of insoluble intranuclear inclusions which disrupt the integrity of the nuclear envelope.
A previous study examined the effect of Ad.TGF-β1 in the knee joints of naïve C57/Bl/6 mice where gene transfer of TGF-β1 to the mouse knee resulted in hyperplasia of the synovium as well as in chondro-osteophyte formation at the chondrosynovial junctions [ 10 ] . The present experiments have shown similar effects on synovial proliferation, but also have extended the murine studies to examine the effects of TGF-β1 in both diseased knee joints and normal knee joints in the rabbit.
Overall, this process resulted in 59% of respondents classified as urban, 18% as suburban and 23% as rural.
[ 37 38 39 ] Subsequent in vivo studies using fluorine 19 magnetic resonance spectroscopy confirmed a three-fold increase in 5-fluoronucleotide (FNuct), the active 5-FU metabolite, following the pre-treatment of animals with MTX [ 32 ] . These observed changes in 5-FU catabolism resulted in a greater anti-tumor activity than MTX given alone or MTX given after 5-FU.
By contrast, co-expression of v-crk with the chimera resulted in reduction in the association of v-crk with endogenous Cas and in induced association of v-crk with the tyrosine phosphorylated Cas 3'SD (Fig.
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